The answers to these questions, of course, depend on many factors such as the specific medications in question, the diseases you have and the amount of alcohol you are planning to drink, as well as your age and general physical condition.
However, if you do choose to drink, pay particular attention to the specific drugs in the table and reading the instructions on your drug labels.Currently, trazodone is the second most commonly prescribed treatment for insomnia.Trazodone is often used as a hypnotic for sleep difficulties even in non-depressed insomniacs.Trazodone's hypnotic properties are due to its antihistaminergic effects at the histamine-1 receptor, alpha 1-adrenergic receptor antagonism, and serotonin 5-HT2 receptor antagonism. Should you only worry about alcohol-drug interactions if you are going to drive?Here are some suggestions: Antibiotics ("Antabuse" reac- tion, causing unpleasant side effects because alcohol cannot be digested) Cefamandole (MANDOL) Cefoperazone (CEFOBID) Cefotetan Ceftriaxone (ROCEPHIN) Furazolidone (FUROXONE) Griseofulvin (FULVICIN, GRIFULVIN V, GRIS-PEG, GRISACTIN) Ketoconazole (NIZORAL) Metronidazole (FLAGYL)** Quinacrine (ATABRINE) Tinidazole (TINDAMAX, FASIGYN) Antidepressants, Tricyclic Amitriptyline (ELAVIL)* Amoxapine (ASCENDIN)** Clomipramine (ANAFRANIL) Desipramine (NORPRAMIN) Doxepin (SINEQUAN)** Imipramine (TOFRANIL, TOFRANIL PM)** Nortriptyline (AVENTYL, PAMELOR) Protriptyline (VIVACTIL) Trimipramine (SURMONTIL) Antidiabetic medications Acetohexamide (DYMELOR)* Chlorpropamide (DIABINESE)* Glimepiride (AMARYL)** Glipizide (GLUCOTROL)** Glyburide (DIABETA, GLYNASE, MICRONASE)** Metformin (GLUCOPHAGE)** Nateglinide (STARLIX)* Pioglitazone (ACTOS)* Repaglinide (PRANDIN)* Rosiglitazone (AVANDIA)* Tolazamide (TOLINASE)** Tolbutamide (ORINASE)** Antihistamines, sedating Azatadine (OPTIMINE, TRINALIN) Azelastine (ASTELIN)* Brompheniramine (DIMETANE) Carbinoxamine Cetirizine (ZYRTEC)** Chlorpheniramine (ALERMINE, CHLOR-TRIMETON) Clemastine (TAVIST-1) Dexchlorpheniramine (POLARAMINE) Diphenhydramine (BENADRYL, DYTAN SUSPENSION, DYTAN-D SUSPENSION, SOMINEX FORMULA) Hydroxyzine (ATARAX, HY-PAM, VISTARIL) Levocabastine (LIVOSTIN) Promethazine (PHENERGAN)** Tripelennamine (PBZ) Triprolidine Antiseizure drugs Carbamazepine (CARBATROL, TEGRETOL) Clonazepam (KLONOPIN) Divalproex (DEPAKENE/DEPAKOTE) Gabapentin (NEURONTIN)** Phenobarbital (LUMINAL, SOLFOTON)** Phenytoin (DILANTIN) Pregabalin (LYRICA)*** (2012) Valproic acid (DEPAKENE) NSAIDs and Aspirin Buffered aspirin (ASCRIPTIN, BUFFERIN) Celecoxib (CELEBREX) Diclofenac (VOLTAREN) Diflunisal (DOLOBID) Etodolac (LODINE) Fenoprofen (NALFON) Flurbiprofen (ANSAID, OCUFEN); Ibuprofen (ADVIL, MEDIPREN, MOTRIN, NUPRIN) Indomethacin (INDOCIN) Ketoprofen (ORUDIS) Ketorolac (TORADOL) Meclofenamate (MECLOMEN) Mefenamic acid (PONSTEL) NSAIDs and Aspirin cont.
EKG at baseline to evaluate for preexisting cardiac conduction abnormalities.
Benefits Mechanism of action Trazodone is a serotonin reuptake inhibitor and is also a 5-HT2 receptor antagonist.
However, in contrast to the SSRIs, trazodone's antidepressant effects may be due to its antagonistic action at the 5-HT2 receptor site.
Polysomnographic studies of people with various kinds of insomnia have found that trazodone's main effect on sleep architecture is an increase in deep slow-wave (stages 3 and 4) sleep.
Comparative efficacy Trazodone versus Zolpidem (Ambien®) Only one high quality comparative study with trazodone has been performed.
adults drink alcohol at least occasionally, so it is not surprising that at one time or another most face questions about alcohol consumption while taking medications: Is it necessary to completely abstain from alcohol, or should you just moderate your alcohol intake?